Journal of Nursing, Education Sciences, and Medical Practice
The Journal of Nursing, Education Sciences, and Medical Practice (JNESMP) (ISSN: 3009-5867) is a peer-reviewed, open-access academic journal disseminates high-quality research, review articles, and case studies in nursing, education sciences, and healthcare practice. JNESMP aims to bridge the gap between research and practice, offering healthcare professionals, educators, researchers, and students a platform to share their findings and insights. Scope and Focus: Nursing: Research and innovations in nursing practice, patient care, nursing education, and professional development. Topics include evidence-based practice, clinical guidelines, patient safety, and nursing ethics. Education Sciences: Studies on curriculum development, teaching methodologies, educational technologies, and assessment in medical and nursing education. Emphasis is placed on improving educational outcomes and professional competencies. Medical Practice: Articles covering a wide range of medical disciplines, focusing on clinical practice, healthcare delivery, patient management, and medical training. Topics include clinical trials, case reports, healthcare policies, and interdisciplinary approaches.
Organophosphate poisoning due to transdermal application of diazinon in a 7-years-old child
Organophosphate compounds remain a major cause of pesticide-related intoxications worldwide. Their toxicity results from inhibition of acetylcholinesterase, leading to accumulation of acetylcholine at synaptic junctions and overstimulation of nicotinic and muscarinic receptors. We report a rare case of severe organophosphate poisoning following transdermal exposure in a seven-year-old girl. The patient developed altered consciousness and generalized seizures after topical application of an agricultural insecticide for the treatment of scalp pediculosis. She received prompt symptomatic and antidotal therapy, with a favorable clinical outcome. This case highlights the potential severity of dermal exposure to organophosphates in children and underscores the importance of public awareness regarding inappropriate domestic use of agricultural pesticides.
Copyright (c) 2025 Redouane El kiri, Hasnae Hoummani, Sahar Amrani Hanchi, Sanae Achour (Author) https://creativecommons.org/licenses/by-nc-nd/4.0
An investigation of risks associated with the handling of anti-cancer drugs by nursing staff in the departments of the oncology hospital of Fez- Morocco: A cross-sectional study
Scientific, technological and organizational advances have led to significant progress in the drug management of cancer patients. However, these anticancer drugs can have risks on healthcare professionals and assessing these risks in all departments of oncology is required for the use of anti-cancer drugs in healthcare settings. The aim of this study is to describe risk prevention measures related to the handling and management of anticancer drugs by nursing staff working at Hassan II University Hospital in Fez HUH-Fez, Morocco. A cross-sectional study. A tested and validated self-administered questionnaire of 30 items was conducted among 28 nurses of HUH-Fez. The response rate to the questionnaire was 96.42%. The study revealed that most nurses did not use sterile medical devices during drug preparation. The study also showed that more than half of the nursing staff (54%) dont rinse the lines at the end of each administration, and that the majority of nurses dont wear personal protective equipment. In terms of environmental protection and health, the study showed that more than half of the nursing staff (52%) were unaware of the risk of exposure to surfaces contaminated by anti-cancer drugs, 85% of participants did not use decontamination kits to clean their premises, and cytotoxic waste was not separated from other hospital waste. The handling of cytotoxic drugs is a high-risk process for the patient, the environment and the personnel handling them. This study showed that measures to prevent risks associated with the handling and management of these drugs by nursing staff in oncology departments are not strictly adhered to. In order to improve working conditions in these units, certain recommendations have been made.
Copyright (c) 2025 Mohamed Hmidani, Inass Sabirou, Youssef Mouacha, Naoual Allali, Zineb El Othmani, Fatima Zahra Milouk, Nabila Chahboun, Mustapha Allali (Author) https://creativecommons.org/licenses/by-nc-nd/4.0
Δ9-Tetrahydrocannabinol and Morphine as Potential Modulators of STAT3 and IL-6 in Ischemic Stroke: A Case Study and In Silico Approaches
Ischemic stroke is a leading cause of mortality and disability worldwide, with inflammation playing a central role in its pathophysiology. STAT3 and IL-6 are key players in the neuroinflammatory response that underlies neuronal injury and repair processes. Δ9-tetrahydrocannabinol (THC), the primary psychoactive in cannabis, and morphine, a widely used opioid, are well known to modulate these pathways. Here, we present a combined case study of ischemic stroke and in silico analyses to assess the involvement of THC and morphine in stroke pathogenesis. The case study concerns a young man with confirmed cannabis and opiate use and acute ischemic stroke. In silico studies reveal that STAT3 is a common target of THC and ischemic stroke, while IL-6 is the key target of morphine in relation to stroke. THC demonstrates a dual capacity to both activate and inhibit the JAK/STAT3 pathway, while IL-6, via JAK/STAT3 signaling, exhibits both neuroprotective and destructive properties in ischemic stroke. Our results highlight the complex interplay between STAT3, IL-6 and external agents such as THC and morphine in stroke pathology. They highlight the need for further experimental studies to validate these molecular interactions and assess the therapeutic and pathological implications of targeting these pathways in the management of ischemic stroke
Copyright (c) 2025 Hasnae Hoummani, Mohamed Chebaibi, Siham Bouchal, Faouzi Belahcen, Sanae Achour (Author) https://creativecommons.org/licenses/by-nc-nd/4.0
Use of ICTE in nursing and health technology: Attitudes and practices of ISPITS teachers in Morocco
Information and Communication Technologies in Education (ICTE) are indispensable pedagogical tools in any quality education system. Their integration significantly changes our relationship with knowledge and its transmission and acquisition methods. This study aims to present the current state of professional and pedagogical use of Information and Communication Technologies by teachers at Morocco's Higher Institutes for Nursing and Health Technology (ISPITS). A quantitative methodological approach was adopted, based mainly on a questionnaire survey of teachers' practices regarding implementing ICTE. The results revealed that most teachers surveyed showed great interest in using ICTE in their teaching practices. However, the integration of these digital tools remains limited for some. This shows that facilitating and reinforcing the integration of ICTE into nursing and health technology training has become an essential requirement.
Copyright (c) 2025 Insaf Mabchour, Kaoutar Mabchour, Samira Reguragui, Youness El abdali, Abdelouahid Merzouki, Aimad Allali (Author) https://creativecommons.org/licenses/by-nc-nd/4.0
Rare Cardiotoxicity in a Child Following Accidental Alphachloralose Ingestion: A Case Study with In-Silico Insights
Cardiotoxicity associated with alphachloralose is poorly understood, and its underlying mechanisms remain unclear. Only a few cases have been reported in the literature. We present the case of a 5-year-old child who experienced moderate alphachloralose poisoning following accidental ingestion. Cardiac involvement was identified through elevated troponin levels, with a favorable outcome following symptomatic treatment. The interaction between alphachloralose and cardiotoxicity was evaluated using in silico methods. Alphachloralose potentially induces cardiotoxicity through 15 key overlapping targets, including STAT3, MMP2, and CASP3, identified via database integration and correlation analysis. STAT3, MMP2, and CASP3 emerge as critical targets in alphachloralose-induced cardiotoxicity, offering potential avenues for therapeutic intervention.
Copyright (c) 2024 Hasnae Hoummani, Hajar El Ammari, Mohamed Chebaibi, Sanae Achour (Author) https://creativecommons.org/licenses/by-nc-nd/4.0
Evaluating Hematological Changes in Hemodialysis Patients: A Retrospective Study in a Moroccan Hospital
This retrospective study investigates hematological changes among hemodialysis patients at the Provincial Hospital Center Mohammed VI of El Haouz, Morocco, with a focus on anemia, hyperleukocytosis, infection, and normocytic anemia, along with their implications. A cohort of 100 patients undergoing regular hemodialysis was examined for severe anemia and signs of infection. Hematological parameters, including hemoglobin, hematocrit, white blood cells, and platelet counts, were systematically analyzed to identify deviations from normal reference ranges. Results showed a high prevalence of severe anemia, with 46% of patients exhibiting hemoglobin levels below 8 g/dL, and 60% of the cases were classified as normocytic anemia, highlighting a critical health concern in this population. Additionally, significant abnormalities in white blood cell counts, indicative of hyperleukocytosis, alongside elevated platelet counts, suggested compromised immune function and increased risks of infection and bleeding, which are common complications among dialysis patients. The study is particularly original as it offers a comprehensive analysis of hematological parameters in a rural Moroccan setting, where such data is scarce, providing critical insights into the unique challenges faced by this population. The findings emphasize the systemic impact of hemodialysis on hematological health, particularly in resource-constrained settings, where access to specialized care is limited. It underscores the importance of regular monitoring and individualized management, including the use of erythropoiesis-stimulating agents, iron supplementation, and tailored dialysis protocols. This research calls for enhanced clinical guidelines and further investigation into optimizing therapeutic approaches to improve the quality of life and outcomes for hemodialysis patients in rural regions.
Copyright (c) 2024 Zakaria El Kodmiri, Bouchra Ghazi, El Houssaine Benaddi, Abdelati Ouamani, Maryame Ahnach (Author) https://creativecommons.org/licenses/by-nc-nd/4.0
Descriptive analysis of risk factors for preterm infants with birth weight
Introduction: Prematurity is defined as a birth occurring before the 37th week of amenorrhea, calculated from the 1st day of the last menstrual period and/or an ultrasound scan performed during the first trimester of pregnancy. Premature birth continues to be the world's leading cause of infant and child mortality, sensorimotor disability, and neurodevelopmental difficulties. Objective: Our work aims to describe the incidence and risk factors of prematurity and compare our results with those of other studies. Materials and methods: This is a cross-sectional, retrospective, descriptive study conducted over two years, from June 1, 2021, to June 30, 2023, at the neonatology and neonatal intensive care unit of CHU HASSAN II in Fez. Statistical analyses were performed using the JAMOVI software. Qualitative variables were expressed as frequencies and percentages, while quantitative variables were presented as means with standard deviations (SD) or medians with interquartile ranges (IQR). Results: The neonatology and neonatal resuscitation department welcomed 241 premature newborns with a birth weight ≤ 1500g, representing 8.80% of all hospitalizations in the department. 127 (53%) were female, and 114 (47%) male. The mean gestational age was 30.6 ± 2.4 weeks of amenorrhea. 71% of newborns (170) were born spontaneously preterm, and 29% (71) induced preterm. Factors associated with prematurity were mainly the threat of preterm delivery (36%), lack of medical follow-up of pregnancy (21%), gravidic hypertension in 18.67%, and gestational diabetes in 5.80% of cases. Conclusion: This study determined the frequency of premature delivery and identified certain risk factors, some of which are already targeted by the national perinatal program. The results of our study are intended to sound the alarm about the need to implement a management plan to improve the monitoring and management of premature pregnancies and births at all levels of care.
Copyright (c) 2024 El Hassan Ouanouche, Safae Rahmouni, Khadija Skalli Houssaini , Soukaina Stati, Driss Oukachou, Fouzia Hmami (Author) https://creativecommons.org/licenses/by-nc-nd/4.0
Clinical and epidemiological profiles of newborns from twin pregnancies in Hassan II University Hospital of Fez, Morocco
Twin pregnancies are high-risk pregnancies, and delivery of twins poses variable difficulties due to the complexity of obstetrical mechanics and the frequency of dystocic presentations. Twin births represent a real public health issue and are responsible for a high rate of perinatal mortality. This study aims to report on newborns' epidemiological, clinical, therapeutic, and evolutionary aspects from twin pregnancies hospitalized in the Neonatal Intensive Care and Neonatology Department of the Hassan II University Hospital, Fez. A cross-sectional, retrospective, and descriptive study was conducted on newborns from twin pregnancies hospitalized in the neonatal and neonatal intensive care unit over two and a half years. Statistical analyses were performed using the JAMOVI software. Qualitative variables were expressed as frequencies and percentages, while quantitative variables were presented as means with standard deviations (SD) or medians with interquartile ranges (IQR). A total of 96 newborns from twin pregnancies were collected. The average maternal age was 29.7 years. Maternal complications during pregnancy were dominated by the threat of premature delivery (38.77%), premature rupture of membranes 5.49%), and urinary and cervicovaginal infectious complications (12.24%).89.8% of deliveries were medicalized, with vaginal delivery being the most common (69.39%).91.67% of newborns were premature, thus dominating neonatal morbidity. The average weight was 1585g +/- 425g.76.04% of newborns presented with neonatal respiratory distress, the most frequent etiology of which was hyaline membrane disease. These neonates presented other complications: neonatal jaundice (62.5%), perinatal anoxo-ischemia (6.25%), and transfusion-transfusion syndrome (6.25%). The neonatal mortality rate was 31.25%, with the leading cause being severe neonatal infection (56.67%). The prevalence of twin pregnancies is on the rise, with a high prevalence of prematurity among newborns, requiring special attention to limit complications.
Copyright (c) 2024 Safae Rahmouni , Khadija Skalli Houssaini , El Hassan Ouanouche, Soukaina Stati , Driss Oukachou , Fouzia Hmami (Author) https://creativecommons.org/licenses/by-nc-nd/4.0
Teaching practices based on the competency-based approach
The competency-based approach is crucial in the teaching process. It requires not only a change in the curricula but also in the pedagogy and practices of the pedagogical actors. The objective of this work is to analyze teachers' practices to understand better the complexity of the role of the trainer and its impact on the problem of skill acquisition. This is a descriptive study with an analytical aim. The study population comprised permanent teachers from the Higher Institute of Nursing Professions and Health Techniques of Rabat. Data collection was done using a questionnaire. Numbers, relative frequencies, and averages were analyzed using the SPSS version 20 program. The study aims to analyze teaching practices to understand better their role in acquiring competencies according to the competency-based approach. The study's results showed that the average age of the study participants was 34±3.8 years, and almost half of them (48.29%) had a long teaching history. In their practice, half of teachers do not plan their lessons according to the CBA. A percentage of 43.10% of teachers say they link theory and practice to attain and integrate skills and specify that they diversify teaching and learning activities and methods. Complex situations are sometimes created by 34.48% and often by 22.41% of the participants. The negotiation and creation of projects are sometimes practiced by 37.93%. Also, 24.14% of respondents always consider the learners' previous knowledge when developing new learning. Only 34.48% of teachers ensure that information and communication technologies are always integrated into teaching and learning activities. The main difficulties reported by teachers in the practice of the competency-based approach were the absence of a competency-based curriculum, the lack of training on the competency-based approach, and the non-adoption of active pedagogy due to a lack of materials and logistical means (37.5% and 29.17%, respectively). The competency-based approach allows for developing and training health professionals. However, its implementation and success depend on establishing the conditions inherent in its application, and the Department of Health should act in this direction.
Principles of the competency-based approach
Higher Institute of Nursing Professions and Health Techniques
Copyright (c) 2024 Salima zerouali, Lhoucine Amasdar, Pr Kaoutara El Omari (Author) https://creativecommons.org/licenses/by-nc-nd/4.0